Top 40 Hits of October 1988
| 1 | Whitney Houston | One Moment In Time |
| 2 | U2 | Desire |
| 3 | The Hollies | He Ain't Heavy, He's My Brother |
| 4 | Enya | Orinoco Flow |
| 5 | Bobby McFerrin | Don't Worry, Be Happy |
| 6 | Womack & Womack | Teardrops |
| 7 | Phil Collins | Groovy Kind Of Love |
| 8 | Erasure | A Little Respect |
| 9 | Rick Astley | She Wants To Dance With Me |
| 10 | Kylie Minogue | Je Ne Sais Pas Pourquoi |
| 11 | Jason Donovan | Nothing Can Divide Us |
| 12 | Wee Papa Girl Rappers | Wee Rule |
| 13 | D Mob featuring Gary Haisman | We Call It Acieed |
| 14 | Inner City featuring Kevin Saunderson | Big Fun |
| 15 | Kim Wilde | Never Trust A Stranger |
| 16 | Bill Withers | Lovely Day |
| 17 | Pet Shop Boys | Domino Dancing |
| 18 | The Pasadenas | Riding On A Train |
| 19 | The Christians | Harvest For The World |
| 20 | TheThe Beatmasters With PP Arnold | Burn It Up |
| 21 | T'Pau | Secret Garden |
| 22 | The Proclaimers | I'm Gonna Be |
| 23 | Alexander O'Neal | Fake '88 |
| 24 | Sinitta | I Don't Believe In Miracles |
| 25 | Yello | The Race |
| 26 | Bananarama | Love Truth And Honesty |
| 27 | Duran Duran | I Don't Want Your Love |
| 28 | Yazz | Stand Up For Your Love Rights |
| 29 | Hazell Dean | Turn It Into Love |
| 30 | Bon Jovi | Bad Medicine |
| 31 | Milli Vanilli | Girl You Know It's True |
| 32 | Gloria Estefan & Miami Sound Machine | Anything For You |
| 33 | Robert Palmer | She Makes My Day |
| 34 | Sabrina | All Of Me |
| 35 | Art Of Noise featuring Tom Jones | Kiss |
| 36 | Bros | I Quit |
| 37 | Royal House | Can You Party |
| 38 | Yazz & The Plastic Population | The Only Way Is Up |
| 39 | Deacon Blue | Real Gone Kid |
| 40 | Jolly Roger | Acid Man |
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