Top 40 Hits of Early October 2000
| 1 | Mariah Carey & Westlife | Against All Odds |
| 2 | Zombie Nation | Kernkraft 400 |
| 3 | The Architechs featuring Nana | Body Groove |
| 4 | All Saints | Black Coffee |
| 5 | Melanie B | Tell Me |
| 6 | Modjo | Lady (Hear Me Tonight) |
| 7 | Anastacia | I'm Outta Love |
| 8 | Pink | Most Girls |
| 9 | Delerium featuring Sarah McLachlan | Silence (Remixes) |
| 10 | Sugababes | Overload |
| 11 | DJ Luck & MC Neat featuring JJ | Ain't No Stoppin' Us |
| 12 | Sonique | Sky |
| 13 | Sisqo | Unleash The Dragon |
| 14 | Billie Piper | Something Deep Inside |
| 15 | Texas | In Demand |
| 16 | Madonna | Music |
| 17 | Vanessa Amorosi | Absolutely Everybody |
| 18 | S Club 7 | Natural |
| 19 | Whitney Houston / Enrique Iglesias | Could I Have This Kiss Forever |
| 20 | Sureal | You Take My Breath Away |
| 21 | Kylie Minogue | On A Night Like This |
| 22 | Eminem | The Way I Am |
| 23 | Spiller | Groovejet (If This Ain't Love) |
| 24 | Roni Size / Reprazent | Who Told You |
| 25 | Wyclef Jean | It Doesn't Matter |
| 26 | Robbie Williams | Rock DJ |
| 27 | Stephen Gately | I Believe |
| 28 | Placebo | Slave To The Wage |
| 29 | Aurora featuring Naimee Coleman | Ordinary World |
| 30 | A1 | Take On Me |
| 31 | Baha Men | Who Let The Dogs Out |
| 32 | Element Four | Big Brother UK TV Theme |
| 33 | Bomfunk MC's | Freestyler |
| 34 | Monsta Boy featuring Denzie | Sorry (I Didn't Know) |
| 35 | The Beautiful South | Closer Than Most |
| 36 | Supersister | Coffee |
| 37 | True Steppers & Dane Bowers featuring Victoria Beckham | Out Of Your Mind |
| 38 | Melanie C | I Turn To You |
| 39 | Scott & Leon | You Used To Hold Me |
| 40 | Richard Blackwood | 1-2-3-4 Get With The Wicked |