Top 40 Hits of September 1981
| 1 | Soft Cell | Tainted Love |
| 2 | Adam & The Ants | Prince Charming |
| 3 | Aneka | Japanese Boy |
| 4 | Ottawan | Hands Up (Give Me Your Heart) |
| 5 | Orchestral Manoeuvres In The Dark | Souvenir |
| 6 | Cliff Richard | Wired For Sound |
| 7 | Electric Light Orchestra | Hold On Tight |
| 8 | The Human League | Love Action (I Believe In Love) |
| 9 | Alvin Stardust | Pretend |
| 10 | The Rolling Stones | Start Me Up |
| 11 | The Pointer Sisters | Slow Hand |
| 12 | UB40 | One In Ten |
| 13 | Gary Numan | She's Got Claws |
| 14 | The Police | Invisible Sun |
| 15 | Diana Ross & Lionel Richie | Endless Love |
| 16 | Modern Romance | Everybody Salsa |
| 17 | Hi Gloss | You'll Never Know |
| 18 | Genesis | Abacab |
| 19 | Ultravox | The Thin Wall |
| 20 | The Tweets | The Birdie Song (Birdie Dance) |
| 21 | Royal Philharmonic Orchestra | Hooked On Classics |
| 22 | Godley & Creme | Under Your Thumb |
| 23 | Lobo | The Caribbean Disco Show |
| 24 | Dollar | Hand Held In Black And White |
| 25 | Bucks Fizz | One Of Those Nights |
| 26 | Randy Crawford | Rainy Night In Georgia |
| 27 | Linx | So This Is Romance |
| 28 | Shakin' Stevens | Green Door |
| 29 | Imagination | In And Out Of Love |
| 30 | Duran Duran | Girls On Film |
| 31 | The Nolans | Chemistry |
| 32 | The Teardrop Explodes | Passionate Friend |
| 33 | The Hollies | Hollidaze |
| 34 | Starsound | Stars On 45 (Volume 3) |
| 35 | Stevie Wonder | Happy Birthday |
| 36 | Depeche Mode | Just Can't Get Enough |
| 37 | Tight Fit | Back To The Sixties |
| 38 | Madness | Shut Up |
| 39 | Rex Smith & Rachel Sweet | Everlasting Love |
| 40 | Ten Pole Tudor | Wunderbar |
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